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Academic journey

My academic journey has led me to ask questions such as:

  • what is the status quo and what could be done to improve it in order to reach vulnerable, at risk populations

  • how could existing systems harness new technologies in order to enact change in a sustainable way

- questions which I'd welcome the opportunity to answer in the future. 

To quickly understand my main research topics, you can view my PhD ceremony, which consists of one hour of questioning on my PhD research. 

Anchor Research

Research

2017 - 2023

Rijksuniversiteit Groningen

University Medical Centrum Groningen, the Netherlands

Marie Skłodowska-Curie Actions

PhD Research

Performed research in the field of tuberculosis (TB):

  • systematic review and meta-analysis on digital health in TB

  • qualitative focus group interviews with medical staff and TB patients on the use of digital health in TB

  • survey of experts (basis for policy development) for latent tuberculosis screening in migrants and use of therapeutic drug monitoring in TB

  • retrospective logistical regression modelling on TB outcomes

  • statistical analysis on the potential use of therapeutic drug monitoring in TB

  • patient reported outcome cohort study on quality of life of TB patients

  • statement paper on the impact of COVID-19 on TB care of migrants

Main supervisors: Prof. Jan-Willem Alffenaar, Prof. Ymkje Stienstra, Dr. Onno Akkerman

Project supervisors: Dr. Sally Hargreaves, Dr. Dominik Zenner, Dr. Adriana Sorete Arbore, Prof.dr. Traian Mihaescu

2013 - 2017

University of Medicine and Pharmacy Iasi, Romania

Research during medical internship

  • Researcher within a consortium funded through the European Lifelong Learning Erasmus programme, the Improvement Science Training for European Healthcare Workers (ISTEW) project. Project website here and conference programme here

  • Member of the Romanian Institute for Healthcare Improvement Science 

  • Clinical trial monitor for a novel Tuberculosis vaccine trial developed as a partnership between the Lung Hospital Iasi, University Medical Centrum Groningen, and the University of Barcelona.

  • Clinical research (clinical study here)

2006-2012

University of Medicine and Pharmacy Iasi, Romania

Research during medical university

  • Medical Imagistics department: study on the opinions of medica students and staff on the educational methods for radiology

  • Bioethics department: literature review and survey study on the perceptions of medical students on working with cadavers

  • Physiology department: animal research on Wisteria rats' arteries

  • Anatomy and forensic departments: internship leading to a small conference paper

Anchor Teaching

Teaching

2023

Warwick University

Clinical research master programme

Online tutoring master students during their clinical research master programme on scientific design, methods, statistics, writing. 

2017 - 2023

Various

Supervision and teaching during the PhD

Supervised a total of four medical master students during their medical research internship. 

Organised and presented courses on research skills and soft skills (presentation skills) in different institutions. 

2013 - 2017 (and 2019)

University of Medicine and Pharmacy Iasi, Romania

Teaching during medical internship

I taught in various medical departments - internal medicine, geriatry, lung science, gastro-enterology, in Romanian, English, and French. 

As a teacher assistant, I would conduct the practicals, which, in Romanian medical school, consist of 3-4 hours of clinical experience - students would learn how to discuss with a patient, perform a clinical exam, formulate diagnosis hypothesis, propose a treatment plan, and report on their findings. 

2007 - 2012

University of Medicine and Pharmacy Iasi, Romania

Teaching during medical university

I began teaching as a volunteer during my collaboration with the Physiology department. I taught practicals to English groups of up to 26 students and, sometimes courses to the whole class of 120 students.

Academic Output

Academic output

Full list here.

Patient reported outcomes of drug susceptible and drug resistant tuberculosis patients in Romania

Margineanu I, Butnaru T, Lam M, Baiceanu D, Dragomir R, Mihaltan F, Sorete Arbore A, Munteanu I, Mahler B, Alffenaar JW, Akkerman O, Stienstra Y

Submitted

 

Treatment outcomes of drug susceptible tuberculosis patients in Romania and Ukraine

Margineanu I, Gafar F, Butnaru T, Baiceanu D, Dragomir R, Semianiv I, Mihaltan F, Munteanu I, Mahler B, Todoriko L, Margineanu S, Stienstra Y,Alffenaar JC, Akkerman O

The International Journal of Tuberculosis and Lung Disease

Submitted

 

Therapeutic drug monitoring in tuberculosis - analysis of opportunities in Romania and Ukraine

Margineanu I, Gafar F, Butnaru T, Baiceanu D, Dragomir R, Semianiv I, Mihaltan F Munteanu I, Mahler B,Todoriko L, Margineanu S, Akkerman O, Stienstra Y, Alffenaar JC

The International Journal of Tuberculosis and Lung Disease

Accepted

 

TB and COVID-19 in migrants – the need to focus on both conditions (link)

Margineanu, I., Mor, Z., Garcia, D., Gilpin, C., Dhawan, S., Ritz, N., Zenner, D.

The International Journal of Tuberculosis and Lung Disease

The International Journal of Tuberculosis and Lung Disease, Volume 25, Number 5, 1 May 2021, pp. 333-335(3)

 

Practices of therapeutic drug monitoring in tuberculosis: an international survey (link)

Margineanu I, Akkerman O, Cattaneo D, Goletti D, Marriott DJE, Migliori GB, Mirzayev F, Peloquin CA, Stienstra Y, Alffenaar JW.

Eur Respir J. 2022 Apr 14;59(4):2102787. doi: 10.1183/13993003.02787-2021. Print 2022 Apr.

 

Country-specific approaches to latent tuberculosis screening targeting migrants in EU/EEA* countries: A survey of national experts, September 2019 to February 2020 (link)

Margineanu I, Rustage K, Noori T, Zenner D, Greenaway C, Pareek M, Akkerman O, Hayward S, Friedland JS, Goletti D, Stienstra Y, Hargreaves S; ESGITM/ESGMYC Study Groups.

Euro Surveill. 2022 Mar;27(12):2002070. doi: 10.2807/1560-7917.ES.2022.27.12.2002070.

 

Patients and Medical Staff Attitudes Toward the Future Inclusion of eHealth in Tuberculosis Management: Perspectives From Six Countries Evaluated using a Qualitative Framework (link)

Margineanu I, Louka C, Vincenti-Gonzalez M, Saktiawati AMI, Schierle J, Abass KM, Akkerman O, Alffenaar JW, Ranchor AV, Stienstra Y.

JMIR Mhealth Uhealth. 2020 Nov 2;8(11):e18156. doi: 10.2196/18156.

 

eHealth in TB clinical management: a systematic review and meta-analysis (link)

Margineanu I, Louka C, Akkerman O, Stienstra Y, Alffenaar JW.

Int J Tuberc Lung Dis. 2022 Dec 1;26(12):1151-1161. doi: 10.5588/ijtld.21.0602.

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